Fig. 4.

Alignment (a) and secondary structures predicted for a putative LV cre in the VPg-encoding gene of the 64-7855 (b) and 87-012 prototype (c) strain, and secondary structures of cre sequences identified in the 2C-encoding gene of poliovirus type 3 (d) and the capsid-encoding region of human rhinovirus type 14 (e) (Goodfellow et al., 2003; McKnight & Lemon, 1998). In (a), shading indicates conserved nucleotides; < and > indicate conserved nucleotides participating in predicted stem structures. The AAA sequence, which is conserved in picornavirus cre, is indicated by asterisks (*) in the alignment and by bold type in secondary structures.