Table 1.

Biological functions and measures of coordinated mRNA expression of the clusters in the pheromone network (fig. S4). EC, expression coherence (53). EA, expression activity (18).

Cluster	Top three enriched GO biological process terms		Corrected P-value	P-value of EC score	P-value of EA score
1	GO:0046907	intracellular transport	1.23E-09	0.711	1
	GO:0051649	establishment of cellular localization	1.23E-09
	GO:0051641	cellular localization	1.71E-09
2	GO:0006457	protein folding	1.41E-04	0.251	0.735
	GO:0042026	protein refolding	1.41E-04
	GO:0000069	kinetochore assembly	8.35E-04
3	GO:0016193	endocytosis	1.73E-06	0.128	1
	GO:0007114	cell budding	1.26E-05
	GO:0051301	cell division	1.26E-05
4	GO:0000074	regulation of progression through cell cycle	2.68E-06	0.421	0.453
	GO:0051726	regulation of cell cycle	2.68E-06
	GO:0006270	DNA replication initiation	3.44E-06
5	GO:0006350	transcription	8.00E-14	0.863	1
	GO:0045449	regulation of transcription	1.94E-12
	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism	7.15E-12
6	GO:0007096	regulation of exit from mitosis	3.52E-07	0.063	1
	GO:0007088	regulation of mitosis	4.45E-07
	GO:0000074	regulation of progression through cell cycle	1.05E-05
7	GO:0048856	anatomical structure development	3.19E-14	0.35	0
	GO:0007148	cell morphogenesis	3.19E-14
	GO:0019236	response to pheromone	1.26E-11
8	GO:0006350	transcription	1.89E-09	0.504	0.35
	GO:0006351	transcription, DNA-dependent	7.90E-09
	GO:0032774	RNA biosynthesis	7.90E-09
9	GO:0000082	G1/S transition of mitotic cell cycle	2.15E-04	0.272	0.008
	GO:0051325	interphase	1.07E-03
	GO:0051329	interphase of mitotic cell cycle	1.07E-03
Full network	GO:0006350	transcription	2.67E-23	0.729	1
	GO:0019222	regulation of metabolism	2.73E-21
	GO:0050791	regulation of physiological process	1.16E-20