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. 2009 Dec 10;8(2):209–226. doi: 10.2203/dose-response.09-016.Nowosielska

TABLE 1.

Relative numbers (percentage of the control value) of the pulmonary L1 sarcoma colonies and cytotoxic activity of the NK cell-enriched splenocytes (NK cells) and IFN-γ- and LPS-stimulated peritoneal macrophages (Mϕ) after single WBI (Fig. 1) of mice with 0.1 or 0.2 Gy X-rays and i.p. injection with anti-asialo GM1 antibody or CGN.

Pulmonary colonies [% of the control value]
Cytotoxic activity of NK cells [% lysis]
Cytotoxic activity of Mϕ [% lysis]
Group PBS Ab CGN PBS Ab PBS CGN
Control 100 147* 401* 7.2 0.5* 29.4 14.6*
0.1 Gy 64* 155* 352* 11.1* 0.3* 40.4* 16.3*
0.2 Gy 68* 137* 387* 11.4* 0.3* 42.1* 17.5*

The parameters were examined on the 14th (pulmonary colonies), 2nd (NK cells), and 3rd (Mϕ) days after single WBI. Control – sham-exposed mice; 0.1 Gy – mice exposed to a single WBI with 0.1 Gy X-rays; 0.2 Gy – mice exposed to a single WBI with 0.2 Gy X-rays; PBS – mice i.p. injected with phosphate buffered saline; Ab – mice i.p. injected with anti-asialo GM1 antibody; CGN – mice i.p. injected with CGN.

*

indicates statistically significant (p<0.05) difference from the control/PBS value.