TABLE 1.
Pulmonary colonies [% of the control value] |
Cytotoxic activity of NK cells [% lysis] |
Cytotoxic activity of Mϕ [% lysis] |
|||||
---|---|---|---|---|---|---|---|
Group | PBS | Ab | CGN | PBS | Ab | PBS | CGN |
Control | 100 | 147* | 401* | 7.2 | 0.5* | 29.4 | 14.6* |
0.1 Gy | 64* | 155* | 352* | 11.1* | 0.3* | 40.4* | 16.3* |
0.2 Gy | 68* | 137* | 387* | 11.4* | 0.3* | 42.1* | 17.5* |
The parameters were examined on the 14th (pulmonary colonies), 2nd (NK cells), and 3rd (Mϕ) days after single WBI. Control – sham-exposed mice; 0.1 Gy – mice exposed to a single WBI with 0.1 Gy X-rays; 0.2 Gy – mice exposed to a single WBI with 0.2 Gy X-rays; PBS – mice i.p. injected with phosphate buffered saline; Ab – mice i.p. injected with anti-asialo GM1 antibody; CGN – mice i.p. injected with CGN.
indicates statistically significant (p<0.05) difference from the control/PBS value.