Table 1.
Inhibition of oocyst proliferation in transgenic mosquitoes after a single blood meal on Plasmodium-infected chickens
| Wild-type | VgR3 | Vg-CecA | Vg-DefA | Vg-CecA/DefA | |
| EXP1 | 116.2* (124–195) 11MG† | 151.7 (99–185) 10MG | 9.2 (5–16) 10MG | 27.2 (5–56) 11MG | 9.3 (4–15) 11MG |
| EXP2 | 192.3 (152–233) 12MG | 182.2 (121–222) 10MG | 11 (6–19) 10MG | 33.8 (6–67) 10MG | 11.1 (6–18) 11MG |
| EXP3 | 155.4 (103–172) 11MG | 7.9 (4–14) 11MG | 17.7 (4–35) 10MG | 6.5 (3–11) 12MG | |
| EXP4 | 126.2 (82–155) 10MG | 7.7 (3–14) 11MG | 14.9 (4–32) 11MG | 4.3 (0–10) 11MG | |
| EXP5 | 146.5 (97–188) 12MG | 9.9 (0–21) 11MG | 20.1 (4–37) 12MG | 4.7 (0–14) 14MG |
EXP1–5—independent experiments utilizing separate cohorts of mosquitoes.
*The mean oocyst number per midgut. The range of observed values is indicated in parentheses.
†The total number of mosquito midguts examined.