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Shh signaling in the embryonic cerebellum. Cerebellar VZ displays Shh signaling activity by E14.5. At E16.5, Shh signaling continues to be apparent along cerebellar VZ, with higher expression in the medial portion. Note that at this stage, there are many positive cells beyond VZ within the cerebellar tissue. β-gal+ cells overlap with BLBP+ cells in E13.5 Ptch1LacZ/+ embryos.
