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. 2010 Apr 16;107(18):8422–8427. doi: 10.1073/pnas.0911838107

Fig. 3.

Fig. 3.

Radial glia cell proliferation is defective in Nestin-cre;Smof/- and Nestin-cre;SmoM2 mutants. (A) Nestin-cre;Smof/- or Nestin-cre;SmoM2 mutants exhibit impaired or augmented BrdU incorporation in BLBP+ or Sox2+ radial glial cells, respectively. (B) Quantification of proliferating radial glial cell number in WT, Nestin-cre;Smof/-, and Nestin-cre;SmoM2 mutants. (C) Ptf1a-expressing cells are essentially not mitotic, indicated by largely nonoverlapping staining after 1-h BrdU pulse in E14.5 WT embryos. Arrow indicates one Ptf1a-expressing cell with weak, punctate BrdU signal that is rarely observed.