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. Author manuscript; available in PMC: 2010 Oct 28.
Published in final edited form as: Sci Transl Med. 2010 Apr 28;2(29):29ra31. doi: 10.1126/scitranslmed.3000928

Fig. 7. Newborn CF piglets fail to eradicate bacteria.

Fig. 7

(A) Percentage of BAL liquid and lung homogenate samples that were sterile (no culturable bacteria) from newborn non-CF and CF pigs. BAL liquid n=20 non-CF and n=11 CF; lung homogenate n=18 non-CF and n=12 CF. Data are from 6 litters. * P < 0.05. (B) Quantitative microbiology on lung homogenate tissue samples. 6-12 h-old piglets were euthanized and lungs were sterilely removed. Each point represents an individual animal. Horizontal line denotes median. (C) Percentage of BAL liquid, trachea, and lung homogenate samples that contained no S. aureus. Samples were obtained from newborn non-CF and CF piglets after intrapulmonary challenge with S. aureus. (* P < 0.05 Chi-square test). (D) Bacteria recovered from tracheal lobe after S. aureus intrapulmonary challenge. Each point represents a different animal. Horizontal line denotes median. Data are from 5 litters. n=15 non-CF and n=11 CF.