Skip to main content
. Author manuscript; available in PMC: 2010 Jun 22.
Published in final edited form as: Circ Cardiovasc Genet. 2009 Oct 19;2(6):591–598. doi: 10.1161/CIRCGENETICS.109.883231

Figure 2.

Figure 2

A major locus for infarct volume maps to distal chromosome 7. The graph presents the results of a genome-wide linkage scan for infarct volume 24 hours after permanent MCA occlusion in 105 (B6×BALB/c) F2 progeny. Chromosomes 1 through X are represented numerically on the x axis. The relative width of the space allotted for each chromosome reflects the relative length of each chromosome. The y axis represents the LOD score. The significant (P<0.05) and suggestive (P<0.63) levels of linkage were determined by 1000 permutation tests. One region of the genome, distal chromosome 7, displays highly significant linkage to the trait, with a LOD score of 11.9. Two loci mapping to chromosome 1 and 8 only reached the P=0.63 suggestive level.