Skip to main content
. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Comp Neurol. 2010 Aug 1;518(15):3046–3064. doi: 10.1002/cne.22379

Figure 11.

Figure 11

A) Scatterplot with a linear fit, showing the frequency of myelinated nerve fiber profiles with degenerating axons in the cingulate bundle and genu of the corpus callosum versus a measure of global cognitive impairment, the cognitive impairment index (CII). An increase in CII, indicating worsening cognitive function, is associated with an increase in the frequency of degenerating axons in the cingulate bundle (p < 0.005) but not in the genu of the corpus callosum (p = 0.2465). B) Scatterplot with a linear fit, showing the frequency of myelinated nerve fiber profiles with altered myelin sheaths in the cingulate bundle and genu of the corpus callosum versus CII. Worsening cognitive function is significantly associated with an increased frequency of altered myelin sheaths in the cingulate bundle (p < 0.001) but not the genu (p = 0.1086).