Figure 4.
Scatterplots with piecewise, linear fits showing: A) The number of myelinated nerve fibers per unit area, and B) the frequency of myelinated nerve fiber profiles with degenerating axons in the cingulate bundle and genu of the corpus callosum of young (<10 years), middle aged (10-20 years), and old (>20 years) rhesus monkeys. In both structures, a decrease in myelinated nerve fibers occurs gradually with age, with none of the three age groups exhibiting a significant change in area number density (A). The frequency of degenerating myelinated axons significantly increases only during middle age in both the genu (p < 0.005) and cingulate bundle (p < 0.05; B).