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. 2010 Mar 30;18(6):1085–1093. doi: 10.1038/mt.2010.46

Figure 6.

Figure 6

Retinal function in control dogs. (a) Bilateral full-field electroretinographic recordings of control dogs. Nonaffected dog NA at 12 months of age, affected dog A7 treated with the AAV2/4RPE65.rpe65 vector at 3 months postinjection, and affected dog A6 treated with the AAV2/4CMV.rpe65 vector at 3 months postinjection. (b) Kinetics of retinal function in control dogs. Nonaffected dog NA at different time points after birth, affected dog A7 treated in the right eye with the AAV2/4RPE65.rpe65 vector, and affected dog A6 treated in the right eye with the AAV2/4CMV.rpe65 vector at different time points postinjection. The b-wave amplitudes of the ERG max. (scotopic) of both eyes were measured at different times and reported in the graphs. Gray, right eye; black, left eye. bi, before injection; ERG, electroretinography; mpi, months postinjection.