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. 2010 Apr 22;59(7):1686–1693. doi: 10.2337/db09-0630

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© 2010 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 2. — The late FM NCX1.3 and -1.7 currents are more sensitive to KB-R7943 inhibition (3 μmol/l) compared with peak currents. Representative recordings of NCX1.3 (A) and -1.7 (C) FM currents before (control) and after the application of 3 μmol/l KB-R7943. Concentration-response curves for NCX1.3 (B) and -1.7 (D) late and peak KB-R7943 FM current inhibition demonstrating that KB-R7943 preferentially inhibits the late FM currents compared with peak FM currents. *P < 0.05, n = 4–10 patches per concentration. 0 = <1 μmol/l Ca²⁺. NCX1 proteins were expressed in tsA201 cells.