FIG. 4.

Pretreating islets with catalytic antioxidant (CA) before allogeneic transplant improves islet function. Islets were incubated with CA for 24 h, and then 300 untreated or CA-treated islets were transplanted into allogeneic recipients. A: Normalization blood glucose of recipients within 2 postoperative days. Significance was tested using a Student t test (**P < 0.05). B: Allograft survival of recipients. ■, untreated islets (n = 5); ▵, CA–treated islets (n = 5). Significance was tested using a log-rank test (P = 0.0132).