. 2010 May 26;10:38. doi: 10.1186/1471-244X-10-38

Table 3.

Relative risk of positive psychotic-like symptoms in relation to estimated dietary intake of fatty acids

Dietary intake g/day·MJ		Positive psychotic-like symptoms ^a

Median	Interquintile range	Low level group		Middle level group					High level group
					Energy adjusted		Multivariate^b			Energy adjusted		Multivariate^b

Marine fatty acids^c		No.		No.	RR	95% CI	RR	95% CI	No.	RR	95% CI	RR	95% CI

0.016	(0.00-0.02)	4478	Ref.	3637					237
0.030	(0.02-0.04)	4606		3587	0.94	0.89-1.00	0.97 ^d	0.91-1.03	177	0.71	0.58-0.87	0.75 ^d	0.61-0.92
0.050	(0.04-0.06)	4733		3538	0.91	0.86-0.97	0.96 ^d	0.90-1.02	176	0.69	0.57-0.85	0.76 ^d	0.61-0.93
0.070	(0.06-0.80)	4594		3633	1.00	0.94-1.06	1.05 ^d	0.98-1.13	227	0.96	0.80-1.16	1.05 ^d	0.85-1.29
Omega-6 fatty acids^e
0.6	(0.1-0.7)	4408	Ref.	3712					261
0.7	(0.6-0.8)	4709		3513	0.88	0.82-0.93	0.88 ^f	0.83-0.94	182	0.64	0.53-0.78	0.67 ^f	0.55-0.82
0.8	(0.7-0.8)	4670		3582	0.90	0.85-0.96	0.91 ^f	0.86-0.97	173	0.62	0.51-0.75	0.66 ^f	0.54-0.81
0.9	(0.9-2.1)	4624		3588	0.92	0.86-0.98	0.93 ^f	0.86-0.99	201	0.73	0.60-0.88	0.78 ^f	0.64-0.97
Omega-3 fatty acids^g
0.14	(0.02-0.17)	4444	Ref.	3663					252
0.18	(0.17-0.20)	4613		3628	0.95	0.89-1.01	0.98 ^b	0.92-1.04	175	0.66	0.54-0.81	0.73 ^h	0.60-0.89
0.21	(0.20-0.22)	4736		3512	0.90	0.84-0.96	0.95 ^b	0.89-1.01	176	0.66	0.53-0.80	0.76 ^h	0.62-0.94
0.26	(0.22-0.93)	4618		3592	0.96	0.90-1.02	1.02 ^b	0.95-1.09	214	0.83	0.69-1.00	1.00 ^h	0.82-1.23

^aParticipants categorized into levels of psychotic-like symptoms; low, middle, high (see methods section)

^bIn the multivariate analysis presented, we initially tested the effects of adjusting also for BMI, level of education, country of birth, smoking, dietary intake of meat, dairy products, fruits, cereals and refined sugar, rheumatoid arthritis, gluten intolerance, diabetes and multivitamin supplement. However, none of these covariates change the estimates substantially, and was therefore not included in the final multivariate model

^cSum of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid

^dAdjusted for age, total energy intake and dietary intake of vitamin B12, alcohol and dietary intake of fat other than eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid

^eSum of arachidonic and linoleic acids

^fAdjusted for age, total energy intake and dietary intake of vitamin B12, alcohol and dietary intake of other than omega-6 fatty acids

^gSum of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid and α-linolenic acid

^hAdjusted for age, total energy intake and dietary intake of vitamin B12, alcohol and dietary intake of other than omega-3 fatty acids