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. Author manuscript; available in PMC: 2010 Jun 22.
Published in final edited form as: Nat Genet. 2001 Nov;29(3):321–325. doi: 10.1038/ng753

Fig. 4.

Fig. 4

Polymorphic DNA marker analysis in families with WBS. Analysis of the WBS-deletion region at 7q11.23 identifies the microdeletion-containing chromosome in WBS probands to be inherited from the parent carrying the inversion. Representative results are shown for three families with WS13 (D7S3197), a polymorphic (TAGA)n repeat marker that resides within the unique 5′ end of GTF2I and, therefore, within the WBS microdeletion (Fig. 1). Proband 8579 shows loss of the paternal allele (8580), whereas probands 9618 and 11106 show loss of the maternal allele (9619 and 11107). In each case, these are the parents that carry the inversion chromosome (see Table 1). P, proband; F, father; M, mother.