Table 4.
False recent seroconverters and protective effect of MC on HIV incidence as calculated using BED and AI in combination
| BED-AI | ||||||
|---|---|---|---|---|---|---|
| BED - AI Cut-off | 0.325 - 31.6 | 0.733 - 80.5 | 0.900 - 90.0 | 1.51 - 94.0 | 1.89 - 96.0 | NC |
| Window period | 65.9d | 159d | 213d | 268d | 300d | NC |
| False LTS (%) | NC | 1/9 (11) | 1/13 (7.7) | 2/16 (13) | 3/27 (11) | NC |
| 95% CI | 1 to 40 | 0.4 to 30 | 2 to 33 | 3 to 26 | ||
| Observed false RS (%) | 0/124 (0) | 2/124 (1.6) | 2/124 (1.6) | 6/124 (4.8) | NC | NC |
| 95% CI | 0 to 2.4 | 0.25 to 5.0 | 0.3 to 5 | 1.9 to 9.6 | ||
| 1Calculated false RS (%) | 0.9 | 2.1 | 2.7 | 3.5 | 3.9 | NC |
| Tested RSs | NC | |||||
| Intervention - Control | 2 - 7 | 8 - 17 | 9-21 | 11 - 30 | 16 - 41 | |
| Uncorrected effect (%) | 73 | 55 | 59 | 65 | 63 | NC |
| 95% CI | NC | -1 to 84 | 8 to 84 | 33 to 85 | 36 to 81 | |
| 2Correction | NC | |||||
| Intervention (%) | 36 | 21 | 24 | 25 | 20 | |
| Control (%) | 15 | 14 | 15 | 13 | 11 | |
| Total (%) | 19 | 16 | 17 | 17 | 13 | |
| Corrected effect (%) | 80 | 59 | 64 | 70 | 67 | NC |
| 95% CI | NC | -2 to 93 | 6 to 92 | 39 to 90 | 38 to 86 |
See table caption of Table 3