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. 2010 Feb 23;18(5):873–880. doi: 10.1038/mt.2010.17

Figure 4.

Figure 4

Hearing sensitivity in decibels of treated and untreated mice at 10 kHz. Auditory-evoked brainstem responses (ABR) recording was performed at 5, 10, 20, 28.3, and 40 kHz on 13–17 animals per group at 3, 6, and 9 months of age. The 10 kHz data are representative of the trends observed at each of the frequencies tested. Each group's mean decibel threshold to detect the audible stimuli is shown at 3, 6, and 9 months of age. Significant differences of treated from untreated MPS IIIB groups are indicated with *P < 0.05 and **P < 0.01. AAV, adeno-associated virus; BMT, bone marrow transplant.