Figure 5.

Vaccination with WW-OVA/Pt-Dd prevents tumor engraftment. C57BL/6 naive mice (N = 5–10) were immunized on days –14 and –7 and challenged s.c. in the opposite flank (day 0) with 1 × 10⁵ B16 or B16-OVA melanoma cells. Tumor sizes were monitored every 2 days for 150 days or until tumors reached 10 mm in diameter. Data show tumor growth curves for individual mice, with number of tumor-free mice indicated in parenthesis. OVA, ovalbumin; PBS, phosphate-buffered saline; Pt-Dd, penton-dodecahedron; s.c., subcutaneous.