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. 2010 Jan 26;18(5):881–887. doi: 10.1038/mt.2009.322

Figure 1.

Figure 1

Effect of activin receptor IIb-shRNA. mdx mice were intramuscularly injected with an AAV-1 vector carrying sh-RNA directed against activin receptor IIb (sh-AcvRIIb). One month after injection, mice were killed, and (a) the tibialis anterior muscles were weighed and (b) the expression level of the targeted mRNA was measured by quantitative RT-PCR. The results obtained with the phosphate-buffered saline-injected contralateral TA (for either the weight or the residual mRNA) were used as references. *P < 0.05; **P < 0.01. Graphs below show result from n = 5 mice for each point. TA, tibialis anterior.