Table 1.

Peptides used to influence ERK1/2 and Akt phosphorylation

Protein source	Domain	Sequence
uPAR*
ECI20	2	H-116ECISCGSSDMSCERGRHQSL135-OH
QCR20	2	H-136QCRSPEEQCLDVVTHWIQEG155-OH
EEG20	2	H-156EEGRPKDDRHLRGCGYLPGC175-OH
LRG20	2	H-166LRGCGYLPGCPGSNGFHNND185-OH
YLP20	2	H-171YLPGCPGSNGFHNNDTFHFL190-OH
PGS20	2	H-176PGSNGFHNNDTFHFLKCCNT195-OH
FHN20	2	H-181FHNNDTFHFLKCCNTTKCNE200-OH
TKC19	2	H-196TKCNEGPILELENLPQNGR214-OH
QCY21	3	H-215QCYSCKGNSTHGCSSEETFLI235-OH
DCR20	3	H-236DCRGPMNQCLATGTHEPKN255-OH
HK†
GKE19	5	402GKEQGHTRRHDWGHEKQRK420
FKL20	5	459FKLDDDLEHQGGHVLDHGHK478
GGH18	5	469GGHVLDHGHKHKHGHGHG486
HVL19	5	471HVLDHGHKHKHGHGHGKHKNKGKK494
HKH20	5	479HKHGHGHGKHKNKGKKNGKH498
FXII‡
YHK9	1	39YHKCTHKGR47

uPAR indicates urokinase plasminogen activator receptor; HK, high molecular weight kininogen; and FXII, factor XII.

^*These peptides are described in Mahdi et al.⁸ The numbering of the amino acids shown represents the location of the amino acid in the mature uPAR protein. Note: the single letter code is used for amino acids.

^†These peptides are described in Hasan et al.¹⁶ The numbering of the amino acids shown represents the location of the amino acid in the mature HK protein.

^‡This peptide is described in Mahdi et al.⁷ The numbering of the amino acids shown represents the location of the amino acid in the mature XII protein.