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Comparison of EP metabolic maps (rat H91) for lactate (a) and EP-hydrate (b), with pyruvate metabolic maps (rat H111) for lactate (c) and pyruvate (d) under optimum imaging conditions. High dose and image delay of 20 sec for pyruvate, slow injection rate and 25-sec image delay for EP. Excellent brain EP-hydrate and lactate distribution observed in (b) and (a). Characteristic large out-of-brain pyruvate signal level is observed following a pyruvate injection (d).
