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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Behav Pharmacol. 2010 Mar;21(2):135–143. doi: 10.1097/FBP.0b013e328337be7e

Figure 5. Effects of PRA on locomotor activity (A) and exploratory activity (B,C).

Figure 5

Nonacclimated, drug-naïve mice were placed in Behavior Pattern Monitor (BPM) chambers immediately after administration of saline vehicle or 0.3, 1.0, or 3.0 mg/kg of PRA. Locomotor and exploratory behavior was measured for 90 minutes, divided into 10 minute time blocks. (a) Dose response of PRA effects on distance traveled (in cm). Mice used were male C57BL/6J. (b) Dose response of PRA effects on number of hole pokes. (c) Dose response of PRA effects on number of rears. Data are mean ± SEM. *p < 0.01, #p < 0.05. (n = 9 mice per dose group)