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. 2010 May 17;107(22):10154–10159. doi: 10.1073/pnas.1005599107

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Fig. 5. — IRF5 is dispensable for collagen-induced arthritis and anti-CII autoantibody production. (A) Hind paws of CII-challenged Irf5^+/+ (filled, n = 7) and Irf5^−/− (empty, n = 8) mice were scored for severity of arthritis. Squares represent the average values from each mouse 5 weeks after the start of the experiment. Averages of each group are given by filled rectangles. (B) ELISA for anti-CII autoantibodies in the sera of mice described in A. Linear range OD450 values for IgM, total IgG, and IgG2a isotypes are shown.