Table 3.
Differential gene expression of the top-20 high-traffic proteins between HF and non-HF patients.
| Protein | t-statistic | P | Traffic |
|---|---|---|---|
| FN1 | -0.99 | NS | 140037.9 |
| PDGFRB | 0.62 | NS | 118789.9 |
| ITGB1 | -0.44 | NS | 107208.2 |
| C3 | 1.12 | NS | 53979.1 |
| COL1A1 | 1.43 | NS | 48837.3 |
| TGFB1 | -1.98 | 0.06 | 45861.8 |
| MMP2 | 0.16 | NS | 43355.8 |
| PTEN | -2.45 | 0.02 | 43018.0 |
| CHGB | 0.27 | NS | 42398.0 |
| ITGB3 | NA | NA | 41256.5 |
| ADAM15 | -0.21 | NS | 36080.8 |
| IL6ST | NA | NA | 35295.1 |
| COL2A1 | NA | NA | 33618.7 |
| TNFSF11 | NA | NA | 32703.6 |
| ITGAV | NA | NA | 31291.3 |
| PDGFRA | -0.65 | NS | 31130.0 |
| LRP1 | -0.37 | NS | 30483.8 |
| SRC | -0.54 | NS | 28672.6 |
| MMP9 | -1.15 | NS | 27463.8 |
| TNF | 1.39 | NS | 27462.7 |
Bold rows highlight known HF biomarkers. t-statistic and P values of differential expression between HF and non-HF patients: 16 samples in each class. NS: Non-significant difference or difference statistically detectable at P > 0.1. 'NA': data not available in our expression dataset. A negative t-statistic means that the gene has a higher expression in the HF class.