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Alignment of nucleotide sequences of the HBPol gene product of HBV genotype D. A-to-T nucleotide substitution occurred at nt 204 in all HBV Kuwaiti isolates (KWT1-16). These substitutions represent unique signature sites for local HBV genotype D isolates (shaded). Representative sequences of genotype D are shown (X59795-ITALY, AJ344116-FRANCE, AY161157-INDIA, AB033559-PAPUA, AB078032-JAPAN, AY090453-SWEDEN, AY741796-IRAN, AB126581-RUSSIA, AB104712-EGYPT and AY721605-TURKEY).
