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. 2010 May 20;29(1):52. doi: 10.1186/1756-9966-29-52

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Copyright ©2010 Zhang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histological examinations of NCIH460 tumors treated by different conditions. The hematoxylin-eosin stain of NCIH460 tumors treated by different conditions, PBS plus GCV treated (A); Ad.null treated (B); Ad.hTERT-E1A-TK alone treated (C). Ad.hTERT-E1A-TK plus GCV treated (D). The necrosis is barely seen in control groups (A and B), while there are obvious necrotic areas and numerous apoptotic bodies in the tumor tissues treated by Ad.hTERT-E1A-TK alone or Ad.hTERT-E1A-TK plus GCV treated (C and D). Original magnification ×400.