Table 5. Chr10 QTL candidate genes with SNPs fitting the haplotype B≠C and A≠C.
| Gene | ID | Introns | PosMed | Microarray FC 4m | Microarray FC 8m | qRT–PCR FC 4m | qRT–PCR FC 8 m | N criteria |
|---|---|---|---|---|---|---|---|---|
|
Heca |
Mm.473073 |
3 |
No |
NP |
NP |
|
|
0 |
|
AC153433.6 |
ENSAMUSG95817 |
3 |
No |
NP |
NP |
|
|
0 |
|
Ccdc28a |
Mm.296565 |
19 |
No |
1 |
1.3 |
|
|
1 |
|
Nhsl1 |
Mm.297971 |
1 |
No |
1 |
1 |
|
|
0 |
|
Hebp2 |
Mm.35551 |
1 |
Yes |
NP |
NP |
1.4 |
1.2 |
1 |
|
Perp |
Mm.28209 |
2 |
Yes |
2.8 |
1 |
1.2 |
1 |
2 |
|
Tnfaip3 |
Mm.116683 |
3 |
Yes |
1 |
1 |
1 |
1.3* |
1 |
|
D10Bwg1379e |
Mm.425612 |
10 |
No |
1 |
1 |
|
|
0 |
|
Olig3 |
Mm.156946 |
8 |
Yes |
NP |
NP |
|
|
1 |
|
Il20ra |
Mm.234667 |
6 |
No |
NP |
NP |
|
|
0 |
|
Pex7 |
Mm.338363 |
1 |
Yes |
0.8 |
1 |
|
|
2 |
|
Map3k5 |
Mm.6595 |
8 |
Yes |
1 |
1 |
1.2 |
0.9 |
1 |
|
Mtap7 |
Mm.20928 |
8 |
Yes |
1 |
1 |
|
|
1 |
|
Bclaf1 |
Mm.294783 |
3 |
No |
1 |
1 |
|
|
0 |
|
Pde7b |
Mm.425617 |
6 |
Yes |
NP |
NP |
|
|
1 |
| Ahi1 | Mm.253280 | 5 | Yes | NP | NP | 1 | 1.1 | 1 |
NP represents not present in the microarray. *: Significant difference (p<0.05) in expression between strains obtained by qRT–PCR. Non-syn: nonsynonymous SNP. Syn represents synonymous SNP.