Table 5.
Multiple linear regression analysis results: Urine pH and acid excretion associations with change of BMD*
| Bone Site: | Unadjusted estimate | p-value | Adjusted estimate | p-value | |
| Urine pH: | |||||
| Femoral Neck |
Coefficient: 95% confidence interval: aR2 : |
0.0034 -0.0004 to 0.0073 0.003 |
0.08 |
0.0018 -0.0025 to 0.0062 0.086 |
0.41 |
| Total hip |
Coefficient: 95% confidence interval: aR2 : |
0.0012 -0.0027 to 0.0051 0.001 |
0.54 |
0.0020 -0.0020 to 0.0066 0.096 |
0.29 |
| Lumbar Spine |
Coefficient: 95% confidence interval: aR2 : |
0.0053 -0.0052 to 0.0111 0.003 |
0.07 |
0.0022 -0.0044 to 0.0089 0.026 |
0.51 |
| Urine Acid excretion: | |||||
| Femoral Neck |
Coefficient: 95% confidence interval: aR2 : |
-0.0001 -0.0002 to -0.00002 0.0062 |
0.026 |
-0.0001 -0.0002 to 0.00001 0.088 |
0.19 |
| Total hip |
Coefficient: 95% confidence interval: aR2 : |
-0.0001 -0.0002 to 0.00005 0.001 |
0.26 |
-0.0001 -0.0002 to 0.0001 0.099 |
0.46 |
| Lumbar Spine |
Coefficient: 95% confidence interval: aR2 : |
-0.0002 -0.0003 to -0.00001 0.005 |
0.041 |
-0.00002 -0.0002 to 0.0002 0.026 |
0.84 |
*The following variables were included in the adjusted models to control for confounding: age, gender, family history of osteoporosis, body mass index (BMI), change in BMI, estrogen status, physical activity, calcium intake, vitamin D status, smoking, kidney disease, urine creatinine, thiazide diuretics, bisphosphonate use and baseline BMD.