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Up-regulation of gene transcription in S. scabiei following clinical ivermectin exposure. Changes in transcription of GST mu 1, GST delta 3 (a) and P-glycoprotein (b) in adult female mites exposed to ivermectin. Pools of female mites were collected from a crusted scabies patient prior to treatment (n = 4), after one dose of ivermectin (IVM, n = 4), and after two doses of IVM (n = 2). **:p < 0.01, ***:p < 0.001.
