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Riboswitches have to communicate binding of the aptamer and the ligand to the expression platform. (A) Recent studies have revealed the structure of the preQ1 riboswitch aptamer–ligand complex from Bacillus subtilis (13–15); however, the response mechanism remains undetermined at the molecular and biophysical level (B). Riboswitch sequence from Fusobacterium nucleatum investigated in this study.
