Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PreQ1 riboswitch response. (A) Secondary structure model. (B) Verification of the equilibrium shift from equally populated, competing hairpins in the expression platform (fold A: fold B = 50∶50) toward dominant formation of the downstream hairpin (fold A′: fold B′ = 20∶80) upon ligand binding by 19F NMR spectroscopy. Conditions: cRNA = 0.2 mM, cpreQ1 = 25 mM, 25 mM sodium arsenate buffer, H2O/D2O = 9/1, pH 6.5, 298 K.
