Table 1.
Frequency of vacA and cagA genotypes in patients positive for H. pylori DNA in dental plaque and stomach
H. pylori genotypes |
Histopathological parametersa |
Endoscopic diagnosisb |
Total | ||||||||||
Stomach |
Dental plaque |
DI |
NA |
IM |
H. pylori |
PU | G (+H) | ||||||
vacA | cagA | C | D | N | 1 | 2/3 | 1 | 2/3 | + | + | |||
s1m1 | + | 42 | 4 | 5 | 21 | 30 | 26 | 25 | 8 | 22 | 7 | 34/(10) | 51 |
s1m1, s2m2 | + | 12 | - | - | 5 | 7 | 6 | 6 | 3 | 5 | - | 10/(2) | 12 |
s2m2 | + | - | - | 4 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2/(1) | 4 |
s2m2 | - | 9 | 4 | 15 | 25 | 3 | 22 | 6 | - | 11 | 1 | 22/(5) | 28 |
Total | 63 | 8 | 24 | 53 | 42 | 56 | 39 | 12 | 39 | 9 | 72/(14) | 95 |
DI: Degree of inflammation; NA: Neutrophilic activity (histopathological scores: 1, light; 2, moderate; 3, intense); IM: Intestinal metaplasia; H. pylori: Helicobacter pylori; G: Gastritis; H: Hiatus hernia; PU: Peptic ulcer; N: Polymerase chain reaction (PCR) negative for H. pylori in dental plaque; C: Identical genotypes in the stomach and dental plaque; D: Distinct genotypes in the stomach and dental plaque.
G tests (Yates) = 16.83, P < 0.001 (DI: s1m1 cagA + x s2m2 cagA-); G tests (Yates) = 4.86, P = 0.027 (NA: s1m1 cagA + x s2m2 cagA-);
G tests (Yates) = 4.36, P = 0.037 (disease: s1m1 cagA + x s2m2 cagA-).