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. Author manuscript; available in PMC: 2010 Jun 24.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2006 Mar 24;291(2):G229–G237. doi: 10.1152/ajpgi.00092.2006

Fig. 1.

Fig. 1

Hepcidin is downregulated in the liver of Hfe-deficient mice in response to iron-deprivation. Hepcidin gene expression in the liver of mice fed a standard diet (SD; light gray) or an iron-deficient diet (−Fe; dark gray) from the C57BL/6 (A) and 129/SvEvTac background (B). Hepcidin mRNA expression was quantified by quantitative RT-PCR (qRT-PCR) and normalized to β-actin. The hepcidin/β-actin ratio is shown. The results are presented as means ± SD (n = 3–6 mice/group). Statistical analysis was performed by 1-way ANOVA; **P < 0.001 for comparison with appropriate control mice (SD diet).