Skip to main content
. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Vet Immunol Immunopathol. 2010 Mar 10;136(1-2):108–115. doi: 10.1016/j.vetimm.2010.03.005

Fig. 4.

Fig. 4

Effect of BTV infection (m.o.i 5) on bPAEC intercellular junctions. Immunofluorescence staining for VE – cadherin (green) and BTV core protein VP7 (red) (1000X). The intercellular junctions of infected ECs remain intact at 6, 12, and 18 hours after infection of the bPAEC monolayers (white arrow heads). At 24 hours cytopathic effect is advanced, however intercellular junctions are both intact (white arrow head) in surviving ECs and have gaps (white arrow) formed between adjacent cells. There is a substantial defect in the monolayer where dead cells have sloughed (white asterisks).