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. Author manuscript; available in PMC: 2011 Apr 13.
Published in final edited form as: Biochemistry. 2010 Apr 13;49(14):3101–3115. doi: 10.1021/bi902183w

Figure 5.

Figure 5

Loop 303-309 from the present study is in green and from 1HX0 (29) is in magenta. Electron difference density, which covers the 1HX0 loop fairly well, was calculated with water molecules in the vicinity of the 1HX0 loop removed from the final model. The density suggests an unmodeled alternate conformation for this loop that is consistent with the loop conformation observed in all the acarbose-derived inhibitor complexes. The loop sequence is Arg303-Gly-His-Gly-Ala-Gly-Gly309. The difference density is contoured at 2.0σ.