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. Author manuscript; available in PMC: 2011 Aug 10.
Published in final edited form as: Eur J Pharmacol. 2010 Apr 2;639(1-3):67–80. doi: 10.1016/j.ejphar.2009.12.040

Table 3.

Summary of effects of chronic metabotropic glutamate receptor 2/3 antagonist on performance in the 5-choice serial reaction time task.

Task measure Pump
Implantation
main effect
LY341495
main effect
Implantation ×
LY341495
interaction
Difference between LY341495
and vehicle groups during pump
exposure in absence of
phencyclidine (post-hoc)
accuracy yes not significant
% correct responses yes P < 0.01
% incorrect responses no not significant
% omissions yes not significant
premature responses no not significant
timeout responses no not significant
latency to correct response no not significant
latency to reward retrieval no not significant
total trials yes not significant

The experimental groups did not differ significantly on any measure before minipump implantation.

⬇: significant decrease; ⬆: significant increase; ↔: no change.