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. Author manuscript; available in PMC: 2011 Aug 10.
Published in final edited form as: Eur J Pharmacol. 2010 Apr 2;639(1-3):67–80. doi: 10.1016/j.ejphar.2009.12.040

Table 4.

Summary of effects of repeated phencyclidine and chronic metabotropic glutamate receptor 2/3 antagonist on performance in the 5-choice serial reaction time task.

Task measure Phencyclidine
main effect
LY341495 main
effect
Phencyclidine ×
LY341495 interaction
Difference between
LY341495 and vehicle
groups during phencyclidine
exposure (post hoc)
accuracy no not significant
% correct responses no not significant
% incorrect responses no not significant
% omissions no not significant
premature responses no not significant
timeout responses yes P < 0.05
latency to correct response no not significant
latency to reward retrieval no not significant
total trials no not significant

The experimental groups did not differ significantly on any measure before minipump implantation and phencyclidine administration.

⬇: significant decrease; ⬆: significant increase; ↔: no change.