Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SELDI TOF MS revealed a decrease in the levels of exosomal Aβ and β-CTF mediated by expression of PS2 mutations. (A-B) SELDI TOF MS using 4G8 antibody revealed the presence of Aβ1-40 peptide (m/z = 4235) (A) and β-CTF (m/z = 11320) in exosomes (B). PS2 mutations reduced the levels of both Aβ1-40 and β-CTF. (PS2 M239I/PS2 T122R vs. PS2 wt, p < 0.01, Student’s t-test).
