Table 4.
SNP genotyping in candidate modifier genes of the DFNB2 phenotype
| Gene | SNP | Genotype V:1 | Genotype V:2 | Genotype V:3 | References |
|---|---|---|---|---|---|
| ATP2B2 (PMCA2) | c.2075G>A (p.V586M) | G/G | G/G | G/G | 21 |
| rs2289274 (C>T) | C/T | C/T | C/T | ||
| USH1C (HARMONIN) | rs1055574 (C>T) | C/T | T/T | C/T | 31 |
| rs2240487 (A>G) | A/G | A/A | A/G | ||
| USH1G (SANS) | rs1013013 (G>A) | G/G | G/G | G/G | 32 |
| rs1558448 (G>C) | G/C | G/C | G/G | ||
| PCDH15 | rs10825114 (G>T) | G/G | G/G | G/G | 33 |
| rs1336190 (A>G) | A/G | A/G | A/G | ||
| WFS1 (WOLFRAMIN) | rs1801213 (C>G) | C/G | C/G | G/G | 34 |
| rs1801206 (C>T) | C/T | C/T | T/T | ||
| DFNM1 | rs2032555 (T>C) | T/C | T/C | T/C | 35 |
| rs12076134 (T>G) | T/G | T/T | G/G | ||
| DFNM2 | rs3735875 (G>A) | G/G | G/G | G/G | 36 |
| rs6991392 (A>G) | A/A | A/A | A/A |