Table 4.
Clinical severity of worst 12-month DSM-IV/CIDI bipolar disorder (BPD) episode with and without frequent mood episodes (FME)
| Any bipolar | Bipolar I | Bipolar II | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FME | No FME | FME | No FME | FME | No FME | ||||||||||||||||
| % | (se) | % | (se) | χ2 | % | (se) | % | (se) | χ2 | % | (se) | % | (se) | χ2 | |||||||
| I. Mania/hypo-mania1 | |||||||||||||||||||||
| Severe/Very Severe | 66.3 | (6.9) | 53.7 | (8.4) | 0.9 | 80.3 | (8.6) | 46.9 | (15.3) | 3.0 | 54.1 | (9.9) | 57.2 | (11.4) | 0.0 | ||||||
| Moderate | 25.2 | (6.7) | 34.7 | (9.4) | 0.2 | 19.7 | (8.6) | 35.3 | (15.2) | 295.9* | 30.0 | (9.6) | 34.4 | (12.1) | 0.7 | ||||||
| Mild | 5.2 | (3.0) | 11.6 | (6.0) | 0.0 | (0.0) | 17.8 | (12.0) | . | 9.7 | (5.5) | 8.5 | (6.6) | ||||||||
| None | 3.3 | (3.0) | 0.0 | (0.0) | . | 0.0 | (0.0) | 0.0 | (0.0) | . | 6.2 | (5.4) | 0.0 | (0.0) | . | ||||||
| (n) | (56) | (30) | (27) | (12) | (29) | (18) | |||||||||||||||
| II. MDE1 | |||||||||||||||||||||
| Severe/Very Severe | 50 | 77.8 | (6.1) | 20 | 79.9 | (7.0) | 0.0 | 20 | 74.1 | (10.5) | 7 | 62.6 | (12.9) | 0.3 | 30 | 80.4 | (7.7) | 13 | 91.1 | (6.4) | 0.5 |
| Moderate | 11 | 19.2 | (5.7) | 5 | 14.5 | (6.6) | 0.3 | 5 | 21.2 | (10.0) | 3 | 23.3 | (14.0) | 0.8 | 6 | 17.7 | (7.3) | 2 | 8.9 | (6.4) | 79.5* |
| Mild | 2 | 3.1 | (2.2) | 2 | 5.5 | (3.7) | . | 1 | 4.8 | (4.7) | 2 | 14.1 | (8.0) | . | 1 | 1.8 | (1.7) | 0 | 0.0 | (0.0) | . |
| None | 0 | 0.0 | (0.0) | 0 | 0.0 | (0.0) | . | 0 | 0.0 | (0.0) | 0 | 0.0 | (0.0) | . | 0 | 0.0 | (0.0) | 0 | 0.0 | (0.0) | . |
| (n) | (63) | (27) | (26) | (12) | (37) | (15) | |||||||||||||||
| III. Either mania/hypo-mania or MDE (higher of two scores)1 | |||||||||||||||||||||
| Severe/Very Severe | 59 | 83.5 | (4.9) | 27 | 63.8 | (8.6) | 4.9* | 26 | 81.8 | (7.9) | 11 | 53.2 | (11.6) | 2.5 | 33 | 84.9 | (6.5) | 16 | 71.6 | (10.9) | 1.9 |
| Moderate | 9 | 12.8 | (4.3) | 14 | 28.8 | (9.0) | 0.5 | 5 | 14.1 | (6.9) | 7 | 32.4 | (14.1) | 0.9 | 4 | 11.8 | (5.8) | 7 | 26.3 | (10.7) | 0.2 |
| Mild | 3 | 3.7 | (2.2) | 4 | 7.3 | (4.6) | . | 1 | 4.1 | (4.0) | 3 | 14.5 | (9.5) | . | 2 | 3.3 | (2.2) | 1 | 2.2 | (2.2) | . |
| None | 0 | 0.0 | (0.0) | 0 | 0.0 | (0.0) | . | 0 | 0.0 | (0.0) | 0 | 0.0 | (0.0) | . | 0 | 0.0 | (0.0) | 0 | 0.0 | (0.0) | . |
| (n)2 | (71) | (45) | (32) | (21) | (39) | (24) | |||||||||||||||
Significant difference between 12-month BPD/FME and other 12-month BPD. Significance tests were based on cumulative categories. The significance tests for “moderate” consequent compare severe-moderate versus mild-none. The models used to test the significance of these differences controlled for age and sex. In the case of the models for any BPD (i.e., BP-I/II), we also included a control for BP-I.
Clinical severity of mania/hypo-mania was assessed with a fully-structured version of the Young Mania Rating Scale. Clinical severity of MDE was assessed with the self-report version of the Quick Inventory of Depressive Symptoms. See the text for a description of cut-points. The results in Part III represent the higher of the two severity scores for respondents who had both mania/hypo-mania and MDE in the past 12 months.
Sample sizes are somewhat smaller than in Table 2 because of missing values on the severity scales.