Table 5.
Severity of role impairment associated with worst 12-month DSM-IV/CIDI bipolar disorder (BPD) episode with and without frequent mood episodes (FME)
| Any bipolar | Bipolar I | Bipolar II | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FME | Other | FME | Other | FME | Other | ||||||||||
| % | (se) | % | (se) | χ2 | % | (se) | % | (se) | χ2 | % | (se) | % | (se) | χ2 | |
| I. Mania/hypo-mania1 | |||||||||||||||
| Severe/Very Severe | 76.1 | (5.6) | 57.9 | (7.0) | 3.1 | 72.5 | (9.3) | 74.1 | (10.9) | 0.0 | 79.4 | (6.9) | 49.3 | (11.1) | 3.9* |
| Moderate | 21.6 | (5.1) | 28.2 | (7.1) | 1.5 | 27.5 | (9.3) | 25.9 | (10.9) | . | 16.1 | (6.0) | 29.5 | (10.1) | 1.5 |
| Mild | 1.4 | (1.4) | 4.0 | (3.9) | 3.0 | 0.0 | (0.0) | 0.0 | (0.0) | . | 2.8 | (2.8) | 6.1 | (5.9) | 3.0 |
| None | 0.9 | (0.9) | 9.8 | (3.8) | . | 0.0 | (0.0) | 0.0 | (0.0) | . | 1.8 | (1.8) | 15.1 | (6.0) | . |
| (n) | (62) | (40) | (31) | (16) | (31) | (24) | |||||||||
| II. MDE1 | |||||||||||||||
| Severe/Very Severe | 90.6 | (4.3) | 90.5 | (5.4) | 0.0 | 90.1 | (5.8) | 87.8 | (8.6) | 0.1 | 90.9 | (4.7) | 92.2 | (7.1) | 0.0 |
| Moderate | 8.2 | (4.1) | 9.5 | (5.4) | 28.0* | 9.9 | (5.8) | 12.2 | (8.6) | . | 6.9 | (4.1) | 7.8 | (7.1) | 31.9* |
| Mild | 1.3 | (1.3) | 0.0 | (0.0) | . | 0.0 | (0.0) | 0.0 | (0.0) | . | 2.2 | (2.2) | 0.0 | (0.0) | . |
| None | 0.0 | (0.0) | 0.0 | (0.0) | . | 0.0 | (0.0) | 0.0 | (0.0) | . | 0.0 | (0.0) | 0.0 | (0.0) | . |
| (n) | (68) | (32) | (29) | (14) | (39) | (18) | |||||||||
| III. Either mania/hypo-mania or MDE (higher of two scores) 1 | |||||||||||||||
| Severe/very severe | 94.0 | (3.4) | 78.1 | (8.9) | 8.3* | 94.8 | 3.6 | 78.1 | 8.9 | 3.9* | 93.2 | 4.1 | 66.8 | 8.4 | 7.9* |
| Moderate | 4.9 | (3.2) | 26.6 | (9.1) | 0.3 | 5.2 | 3.6 | 21.9 | 8.9 | . | 4.6 | 3.5 | 26.6 | 9.1 | 0.3 |
| Mild | 1.2 | (1.2) | 2.6 | (2.5) | 93.8* | 0 | 0 | 0 | 0 | . | 2.1 | 2.1 | 2.6 | 2.5 | 98.6* |
| None | 0 | 0 | 4.1 | (4.3) | . | 0 | 0 | 0 | 0 | . | 0 | 0 | 4.1 | 4.3 | . |
| (n)12 | (76) | (56) | (35) | (26) | (41) | (30) | |||||||||
Significant difference between 12-month BPD/FME and other 12-month BPD. Significance tests were based on cumulative categories. The significance tests for “moderate” consequent compare severe-moderate versus mild-none. The models used to test the significance of these differences controlled for age and sex. In the case of the models for any BPD (i.e., BP-I/II), we also included a control for BP-I.
Clinical severity was assessed with an expanded version of the Sheehan Disability Scales (SDS). The results represent the highest severity score across the SDS domains. The results in Part III represent the higher of the two severity scores for respondents who had both mania/hypo-mania and MDE in the past 12 months.
Sample sizes are somewhat smaller than in Table 2 because of missing values on the severity scales.