Table 1.
Baseline characteristics according to migraine categories among participants in the Women’s Health Study (n=27,840)*
| No migraine history (N=22,715) | Active migraine with aura (N=1,434) | Active migraine without aura (N=2,176) | Prior migraine (N=1,515) | P value† | |
|---|---|---|---|---|---|
| Mean age, years (SE) | 54.9 (0.05) | 53.2 (0.19) | 52.6 (0.15) | 55.5 (0.18) | <0.0001 |
| Mean body mass index, kg/m2 (SE) | 25.9 (0.03) | 25.8 (0.13) | 26.2 (0.11) | 26.1 (0.13) | 0.02 |
| Mean low density cholesterol (LDL), mg/dL (SE) | 123.9 (0.22) | 124.6 (0.89) | 124.7 (0.73) | 127.1 (0.87) | 0.003 |
| Mean high density cholesterol (HDL), mg/dL (SE) | 53.9 (0.10) | 53.1 (0.40) | 53.2 (0.32) | 52.6 (0.39) | 0.001 |
| History of diabetes | 2.5 | 1.8 | 1.6 | 2.6 | 0.21 |
| History of hypertension | 24.6 | 25.5 | 26.0 | 30.3 | <0.0001 |
| Smoking | |||||
| Never | 51.3 | 52.7 | 56.3 | 50.6 | |
| Past | 37.1 | 37.3 | 34.5 | 35.4 | |
| Current <15 cigarettes/day | 4.4 | 3.9 | 3.5 | 5.2 | |
| Current ≥15 cigarettes/day | 7.3 | 6.2 | 5.8 | 8.8 | 0.05 |
| Alcohol consumption | |||||
| Rarely/never | 43.5 | 48.3 | 47.4 | 45.0 | |
| 1–3 drinks/month | 13.1 | 13.1 | 15.4 | 14.2 | |
| 1–6 drinks/week | 32.7 | 30.2 | 30.1 | 30.5 | |
| ≥1 drink/day | 10.8 | 8.3 | 7.1 | 10.3 | <0.0001 |
| Physical activity | |||||
| Rarely/never | 37.0 | 38.3 | 39.4 | 39.2 | |
| <1/week | 19.2 | 20.4 | 21.7 | 20.1 | |
| 1–3/week | 32.3 | 30.7 | 29.2 | 29.5 | |
| ≥4/week | 11.6 | 10.7 | 9.7 | 11.3 | <0.0001 |
| Postmenopausal hormone therapy | |||||
| Never | 49.6 | 38.9 | 44.9 | 46.1 | |
| Past | 8.7 | 10.1 | 8.5 | 10.4 | |
| Current | 41.7 | 50.9 | 46.6 | 43.6 | <0.0001 |
| History of oral contraceptive use | |||||
| No | 30.6 | 27.0 | 28.4 | 27.6 | |
| Yes | 69.0 | 72.2 | 71.4 | 71.7 | |
| Not sure | 0.4 | 0.8 | 0.2 | 0.7 | 0.0006 |
| Family history of myocardial infarction prior to age 60 | 11.4 | 12.8 | 11.8 | 12.4 | 0.33 |
*
Data are expressed as age-adjusted percentages unless otherwise stated. Percentages may not add up to 100 due to rounding or missing values.
†
P values were calculated from 3 df tests of general linear models for continuous variables and Mantel-Haenszel chi-square tests for categorical variables.