AUC extrapolated |
percent of the AUC extrapolated to infinity |
AUCinf/Dose |
the area under the curve from 0 to infinity per dose administered |
AUCinf |
area under the curve from time 0 to infinity |
AUMCinf |
area under the first moment curve from time 0 to infinity |
Cl/F |
plasma clearance per fraction of the dose absorbed |
CMAX |
maximum plasma concentration |
CMAX/Dose |
maximum plasma concentration per dose administered |
T ½λz |
terminal half-life |
λz |
first-order rate constant |
MRTinf |
mean residence time extrapolated to infinity |
TMAX |
time to maximum plasma concentration |
Vz/F |
apparent volume of distribution of the area fraction of the dose absorbed |
Relative F |
relative fraction of the dose absorbed for each oral dose rate |