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. Author manuscript; available in PMC: 2011 Jun 8.
Published in final edited form as: Mol Cancer Res. 2010 Jun 8;8(6):873–884. doi: 10.1158/1541-7786.MCR-09-0494

Figure 3. Defective autophagy sensitizes mammary tumor cells to ER stressors and proteasome inhibitors.

Figure 3

MTT assays showing sensitivity of Bcl-2-expressing beclin 1+/+ (blue) and beclin 1+/− (red) iMMECs to increasing concentrations of epoxomycin (left column) and tunicamycin (right column) after 2 days of metabolic stress (A), and after a 2-day recovery following metabolic stress for 3 days (B) and 5 days (C). Data is presented as mean ± SD. p-values were calculated by two way ANOVA.

***, <0.001; **, <0.01; *, <0.05.