Table 2.

Pancreas-specific proteins identified by our GeLC-MS/MS analysis that are present in ePFT collected samples. References in the right-most column are of published pancreatic fluid studies in which the specified protein was identified.

Enterez GeneID	Protein name	Subcellular location	Molecular function	No. of peptides	Mascot score	Previously identified
AMY2B	amylase, alpha 2B	extracellular space	enzyme	41	101	[4, 7, 10]
ANPEP	aminopeptidase N	extracellular space	peptidase	14	80	[4]
CEL	carboxyl ester lipase	extracellular space	enzyme	24	107	[7, 10]
CLPS	colipase, pancreatic	extracellular space	enzyme	6	73	[7, 9]
CPA1	carboxypeptidase A1	extracellular space	peptidase	19	108	[4, 7]
CPA2	carboxypeptidase A2	extracellular space	peptidase	7	95	[4, 7, 10]
CTRB1	chymotrypsinogen B1	extracellular space	peptidase	1	28	[4, 7, 9, 10]
CTRC	chymotrypsin C (caldecrin)	extracellular space	peptidase	11	107	[4, 7]
CTRL	chymotrypsin-like	extracellular space	peptidase	8	61	[7]
ELA2A	elastase 2A	extracellular space	peptidase	16	93	[4, 7, 10]
ELA3B	elastase 3B, pancreatic	extracellular space	peptidase	13	92	[4, 7, 9, 10]
KLK1	kallikrein 1	unknown	peptidase	3	68	[10]
PLA2G1B	phospholipase A2	extracellular space	enzyme	5	69	[4, 7, 9]
PNLIP	pancreatic lipase	extracellular space	enzyme	22	111	[10]
PNLIPRP1	pancreatic lipase-related protein 1	extracellular space	enzyme	1	21	[7, 9]
PRSS1	protease, serine, 1 (trypsin 1)	extracellular space	peptidase	12	90	[4, 7, 9, 10]
PRSS2	protease, serine, 2 (trypsin 2)	extracellular space	peptidase	6	101	[4, 7, 10]
PRSS3	protease, serine, 3	extracellular space	peptidase	6	90	[7, 10]
SERPINA1	alpha-1 antitrypsin	extracellular space	inhibitor	20	129	[7, 10]
SERPINA3	alpha-1-antichymotrypsin	extracellular space	inhibitor	9	96	[7, 10]