Table 2.
Unadjusted linear regression of Fontan Functional Score on each independent variable (405 subjects).
| Variables | R2 | Estimate | Mean | p |
|---|---|---|---|---|
| Demographics | ||||
| Race | 0.008 | 0.216 | ||
| White | 1.04 | 50.1 | ||
| Black | −3.93 | 45.2 | ||
| Other | – | 49.1 | ||
| Male | 0.001 | 1.03 | 0.566 | |
| Parental highest grade of school | 0.019 | 0.109 | ||
| Some high school or less | −4.25 | 47.1 | ||
| High school graduate/GED | 1.04 | 52.4 | ||
| Vocational school, some college | −4.77 | 46.6 | ||
| 4 year college graduate | −1.08 | 50.3 | ||
| Graduate degree | – | 51.4 | ||
| Annual household income, $20K increments | 0.027 | 1.76 | 0.001 | |
| Ventricular type | 0.022 | 0.011 | ||
| Right | – | 45.9 | ||
| Left | 4.79 | 50.7 | ||
| Mixed | 7.19 | 53.1 | ||
| Pre-Fontan end-diastolic pressure, mmHg | 0.041 | −1.08 | < 0.001 | |
| Pre-Fontan oxygen saturation, % | 0.019 | 0.50 | 0.005 | |
| Superior cavopulmonary anastomisis: | ||||
| Yes | 0.020 | 5.68 | 50.9 | 0.004 |
| No | 45.2 | |||
| Age at unloading surgery | 0.022 | −1.68 | 0.003 | |
| Moderate/Severe atrioventricular valvar regurgitation: | ||||
| Yes | 0.003 | −1.85 | 45.8 | 0.502 |
| No | 2.22 | 49.8 | ||
| Unknown | – | 47.6 | ||
| Number of pulmonary arterial surgeries | 0.001 | −0.74 | 0.546 | |
| Age at Fontan, year | 0.005 | −0.62 | 0.157 | |
| Weight for age z score at Fontan | 0.001 | 0.55 | 0.446 | |
| Surgical fenestration: | ||||
| Yes | 0.004 | 2.35 | 50.2 | 0.202 |
| No | – | 47.9 | ||
| Type of Fontan | 0.032 | 0.011 | ||
| Atriopulmonary connection | – | 46.6 | ||
| Total cavopulmonary connection intracardiac lateral tunnel | 2.25 | 48.9 | ||
| Total cavopulmonary connection extracardiac lateral tunnel | 6.59 | 53.2 | ||
| Total cavopulmonary connection extracardiac conduit | 7.86 | 54.5 | ||
| Other | −11.3 | 35.3 | ||
| Cardpulmonary bypass time, minutes | 0.002 | −0.02 | 0.347 | |
| Length of hospital stay, days | 0.009 | −0.09 | 0.062 | |
| Log transformed length of stay | 0.018 | −3.62 | 0.007 | |
| Arrhythmias: | ||||
| Yes | 0.034 | −7.93 | 43.2 | < 0.001 |
| No | – | 51.1 | ||
| Currently on pacemaker: | ||||
| Yes | 0.021 | −7.73 | 42.7 | 0.004 |
| No | – | 50.4 | ||
| Post-Fontan surgeries ≥2 | 0.004 | |||
| Yes | 0.020 | −14.9 | 34.9 | |
| No | – | 49.9 | ||
| Number of post-Fontan catheterization interventions | 0.011 | −1.68 | 0.033 | |
| Number of years since Fontan | 0.013 | −0.59 | 0.023 | |
| Number of years since Fontan categorized | 0.038 | < 0.001 | ||
| Less than 6 years | 4.91 | 49.3 | ||
| 6 to 11 years | 8.16 | 52.5 | ||
| Greater than or equal to 11 years | – | 44.4 | ||