Table 1. Characteristics of participants biopsied for the first time during Rotterdam screening rounds 2-3. Values are frequency (%) or median (interquartile range).

	No cancer n=1113	Cancer n=388
Biopsy round
Round 2	936 (84%)	324 (84%)
Round 3	177 (16%)	64 (16%)
Age	67 (63, 71)	67 (64, 71)
Total PSA, ng/mL	3.80 (3.30, 4.80)	4.00 (3.40, 5.20)
Free PSA, ng/mL	0.84 (0.66, 1.10)	0.75 (0.58, 1.02)
Intact PSA, ng/mL	0.47 (0.36, 0.62)	0.49 (0.37, 0.67)
hK2, ng/mL	0.059 (0.041, 0.082)	0.073 (0.051, 0.101)
Abnormal DRE	194 (17%)	121 (31%)
Biopsy Gleason grade
≤6	--	297 (77%)
7	--	78 (20%)
≥ 8	--	13 (3%)
Clinical stage
T1C	--	236 (61%)
T2	--	138 (36%)
T3	--	14 (4%)