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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Neurobiol Dis. 2010 Mar 27;39(2):127–137. doi: 10.1016/j.nbd.2010.03.016

Figure 7. Expression of TNFα and IGF-1 mRNA during demyelination and remyelination in placebo and E2 treated mice.

Figure 7

A. Real-time PCR analysis of TNFα mRNA. Results show the expected upregulation during demyelination in placebo-treated mice, which is reduced by approximately half in E2-treated mice. All samples are normalized to the no cuprizone placebo group.

B. Real-time PCR analysis of IGF-1 mRNA. Results show the expected upregulation during demyelination in placebo-treated mice, which is dramatically reduced in E2-treated mice. All samples are normalized to the no cuprizone placebo group.