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. 2010 Jun;51(6):2860–2864. doi: 10.1167/iovs.09-4500

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Figure 1. — AA modulates MMP-2 and MMP-9 activity in LH_BETAT_AG transgenic RB. A single subconjunctival injection of 300 mg AA was administered in the right eye (T) of the LH_BETAT_AG transgenic RB mice, while the right fellow eye (F) remained untreated. Whole eye extracts were analyzed by gel zymography to measure MMP-2 () and MMP-9 (■) activities at 24 hours, 48 hours, and 1 week after injection. Top: gelatin zymogram from a representative experiment. Mouse recombinant MMP-9 and MMP-2 were used as positive controls (M). Bottom: average results of three independent gel zymograms. Error bars represent standard deviations from the mean. WT, wild-type; RB, LH_BETAT_AG.

Inline graphic — AA modulates MMP-2 and MMP-9 activity in LH_BETAT_AG transgenic RB. A single subconjunctival injection of 300 mg AA was administered in the right eye (T) of the LH_BETAT_AG transgenic RB mice, while the right fellow eye (F) remained untreated. Whole eye extracts were analyzed by gel zymography to measure MMP-2 () and MMP-9 (■) activities at 24 hours, 48 hours, and 1 week after injection. Top: gelatin zymogram from a representative experiment. Mouse recombinant MMP-9 and MMP-2 were used as positive controls (M). Bottom: average results of three independent gel zymograms. Error bars represent standard deviations from the mean. WT, wild-type; RB, LH_BETAT_AG.