Table 2.
Gene Microarray Showing the Effects of miR-146a on Gene Expressions in HTM Cells
| Gene Symbol | Change (x-fold) ([146a] vs. [ConM]) | Unigene* | P | Microcosm | PicTar-Vert | Targetscan |
|---|---|---|---|---|---|---|
| IRAK1 | −4.28 | Hs.522819 | 0.0011 | T | T | T |
| IL11 | −4.14 | Hs.467304 | 0.035 | |||
| PPP2R1B | −3.8 | Hs.584790 | 0.012 | |||
| GALNT10 | −3.49 | Hs.651323 | 0.0033 | T | ||
| IL8 | −3.32 | Hs.551925 | 6.89E-04 | |||
| SLC10A3 | −3.031 | Hs.522826 | 0.0038 | T | T | T |
| HAS1 | −2.74 | Hs.57697 | 0.049 | T | T | |
| SERPINE1/PAI-1 | −2.74 | Hs.414795 | 0.0022 | |||
| MANIC1 | +2.54 | Hs.197043 | 0.026 | |||
| PHKB | −2.54 | Hs.78060 | 0.0038 | T | T | |
| SLCIA1 | −2.52 | Hs.444915 | 0.0023 | T | T | |
| CXCL3 | −2.47 | Hs.89690 | 9.42E-04 | |||
| CXCL6 | −2.39 | Hs.164021 | 0.0048 | |||
| HYOU1 | −2.33 | Hs.277704 | 0.0062 | |||
| CCL2 | −2.31 | Hs.303649 | 0.014 | |||
| TIMMI7B | −2.3 | Hs.30570 | 8.57E-04 | T | ||
| HAS2 | −2.21 | Hs.159226 | T | T | ||
| ADAM19 | −2.16 | Hs.483944 | 0.011 | |||
| WSB2 | −2.12 | Hs.506985 | 0.006 | |||
| SLC2A3 | −2.11 | Hs.419240 | 0.022 | T | ||
| RCAN1 | −2.10 | Hs.282326 | 0.0024 | |||
| SRPRB | −2.10 | Hs.584950 | 0.0038 | T | T | |
| CCL20 | −2.09 | Hs.75498 | 0.027 | |||
| PTGS1 | −2.09 | Hs.201978 | 0.0049 | |||
| CARD10 | −2.06 | Hs.57973 | 0.041 | T | T | |
| NR4A2 | −2.06 | Hs.563344 | ||||
| LIF | −2.06 | Hs.2250 | 0.044 | |||
| IL6 | −2.05 | Hs.654458 | ||||
| XYLT1 | −2.03 | Hs.22907 | 0.011 | |||
| PTHLH | −2.02 | Hs.591159 | ||||
| RY1 | −2.00 | Hs.54649 | 0.0018 |
*
UniGene, National Center for Biotechnology Information, Bethesda, MD; http://www.ncbi.nlm.nih.gov/UniGene.